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Literature summary extracted from
- Shugoshin-PP2A counteracts casein-kinase-1-dependent cleavage of Rec8 by separase (2010), Nat. Cell Biol., 12, 500-506.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.49 | Rec8 + H2O | Homo sapiens | the phosphorylations of Rec8 at S412 and the surrounding sites, which are most probably dependent on CK1, are essential for the cleavability of Rec8 by separase | fragments of Rec8 | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.49 | Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.49 | Rec8 + H2O | the phosphorylations of Rec8 at S412 and the surrounding sites, which are most probably dependent on CK1, are essential for the cleavability of Rec8 by separase | Homo sapiens | fragments of Rec8 | - |
? | |
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Release 2023.1 (January 2023)
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